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Journal : Diponegoro International Medical Journal (DIMJ)

Correlation between Prolactin Serum with Neutrophil Lymphocyte Ratio (NLR) in Systemic Inflammatory Response Syndrome Dwi Retnoningrum; Meita Hendrianingtyas; Hermawan Istiadi; Ardhea Jaludamascena
Diponegoro International Medical Journal Vol 2, No 1 (2021): July
Publisher : Faculty of Medicine, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dimj.v2i1.9546

Abstract

Background: Systemic inflammatory response syndrome (SIRS) is a state of systemic inflammatory activation by various causes. SIRS have a high mortality rate. Prolactin is known to regulate cellular function of immune system.  Neutrophil-lymphocyte ratio (NLR) is simple, cost effective and easy parameter that currently used as inflammation marker.Objective: The aims of this study is to determine the correlation between prolactin serum with NLR in SIRS patients.Methods: A cross sectional study was conducted on 50 clinically SIRS patients. Prolactin serum was measured by enzyme linked immunosorbent assay (ELISA) and NLR was calculated manually from absolute neutrophil and lymphocyte count measured by automatic hematology analyzer. Non-parametric Spearman test was used to analyze the correlation between prolactin with NLR.Results: Median value of serum prolactin level was 11.32 ng/mL (2.76-194.81), whereas the mean value NLR was 16.36 ± 11.58. The correlation between prolactin levels with NLR was r = 0.345, p = 0.014.Conclusion: There is a weak positive significant correlation between prolactin with neutrophil lymphocyte ratio in SIRS
The Effect of Forward Leaning and Pursed Lips Breathing Exercises on The Value of Oxygen Saturation in Adult Smokers Muhammad Nurul Amin; Erna Setiawati; Rahmi Isma Asmara Putri; Meita Hendrianingtyas
Diponegoro International Medical Journal Vol 1, No 1 (2020): July
Publisher : Faculty of Medicine, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dimj.v1i1.7940

Abstract

Background: Smoking which is a lifestyle trend continues to increase and take its toll each year. Cigarettes have chemical compounds. Which has toxic and carcinogenic effects that can cause respiratory, cardiovascular, and other irritants. This can affect the distribution of oxygen to the body tissues. Forward leaning and PLB exercises can help maximize breathing thereby improving tissue oxygen distribution. Objective: To determine the differences in oxygen saturation of adult smokers before and after practice forward leaning and pursed lips breathing.Methods: This study used a quasi-experimental method with two group pre-post test design. The research subjects were 20 male respondents, the place of implementation at the Faculty of Medicine, Diponegoro University, Semarang. Research procedures included CKD and PLB exercises in the respondent group.Results: Analysis using the Wilcoxon test obtained significant results, with p values <0.05 on acute and chronic effects after CKD and PLB exercises were performed on 20 respondents Conclusion: A significant result in the oxygen saturation value of the group with PLB and CKD treatment with the PLB group before and after exercise on acute and chronic effects in adult smokers